Signe Bruun Munksgaard

‍Hovedpinespecialist og neurolog (PhD, speciallæge) hos Hemi
Signe Bruun Munksgaard

Ekspertiseområder

Diagnosticering og behandling af hovedpinesygdomme, både migræne og spændingshovedpine, men også indenfor mere sjældne typer hovedpine.

Personlig tilgang til behandling

Det er alene patienten, der oplever smerterne og kan beskrive symptomerne. Derfor er samtalen om symptomerne og hvilke ønsker patienten har for behandling vigtig, for vi kan stille den rigtige diagnose og finde den rette behandling for den enkelte.

Uddannelse

2019: Speciallæge i Neurologi

2008 - 2013: Ph.D, Københavns Universitet, Dansk Hovedpine Center

2001 - 2008: Medicin studiet, Københavns Universitet

Erfaring

2023-: Hovedpinespecialist og neurolog, Hemi Hovedpineklinik

2021-: Afdelingslæge med ledelsesansvar for hovedpineklinikken og med specialeområder i hovedpine og akut neurologi inkl. trombolyse, Bispebjerg Hospital, neurologisk afdeling

2019 - 2021: Afdelingslæge med specialeområder i hovedpine og akut neurologi inkl. trombolyse, Rigshospitalet/Dansk Hovedpinecenter

2015 - 2019: Speciallægeuddannelse i neurologi

-Bispebjerg Hospital, neurologisk afdeling

-Rigshospitalet, neurokirurgisk afdeling

-Region Hovedstadens Psykiatri, Nordsjælland

-Rigshospitalet, neurofysiologisk afdeling

-Sjællands Universitetshospital, Roskilde, neurologisk afdeling

-Rigshospitalet, neurologisk afdeling

-Bispebjerg Hospital, neurologisk afdeling

2015 - 2015: Uklassificeret reservelæge, Herlev Hospital, neurologisk afdeling

2015 - 2015: Uklassificeret reservelæge, Glostrup Hospital, neurologisk afdeling

2014 - 2014: Introduktionsstilling i neurologi. Glostrup Hospital, neurologisk afdeling

2012 - 2013: KBU

-Sygehus Sønderjylland, medicinsk afdeling, Haderslev

-Psykiatrien i Region Syddanmark, psykiatrisk afdeling, Haderslev

2008 - 2012: Ph.D studerende, Dansk Hovedpinecenter

2007 - 2008: Deltidsansat som medicinstuderende tilknyttet forskning i migræne, Dansk Hovedpinecenter

Forskningsinteresser

Involveret i hovedpineforskning siden 2008. Primært indenfor medicinoverforbrugshovedpine - og her både i forhold til behandling, men også i de smertemekanismer der ligger bag både medicinoverforbrugshovedpine samt migræne og spændingshovedpine. 

Treatment of medication overuse headache: Effect and predictors after 1 year-A randomized controlled trial.

Carlsen LN, Rouw C, Westergaard ML, Nielsen M, Munksgaard SB, Bendtsen L, Jensen RH.

Headache. 2021 Jul;61(7):1112-1122.

 

Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020.

Schytz HW, Amin FM, Jensen RH, Carlsen L, Maarbjerg S, Lund N, Aegidius K, Thomsen LL, Bach FW, Beier D, Johansen H, Hansen JM, Kasch H, Munksgaard SB, Poulsen L, Sørensen PS, Schmidt-Hansen PT, Cvetkovic VV, Ashina M, Bendtsen L.

J Headache Pain. 2021 Apr 8;22(1):22.

 

Dependence-like behaviour in patients treated for medication overuse headache: A prospective open-label randomized controlled trial.

Rouw C, Munksgaard SB, Engelstoft IMS, Nielsen M, Westergaard ML, Jensen RH, Bendtsen L, Carlsen LN.

Eur J Pain. 2021 Apr;25(4):852-861.

 

Comparison of 3 Treatment Strategies for Medication Overuse Headache: A Randomized Clinical Trial.

Carlsen LN, Munksgaard SB, Nielsen M, Engelstoft IMS, Westergaard ML, Bendtsen L, Jensen RH.

JAMA Neurol. 2020 Sep 1;77(9):1069-1078.

 

Complete withdrawal is the most feasible treatment for medication-overuse headache: A randomized controlled open-label trial.

Engelstoft IMS, Carlsen LN, Munksgaard SB, Nielsen M, Jensen RH, Bendtsen L.

Eur J Pain. 2019 Jul;23(6):1162-1170.

 

Complete withdrawal is the most effective approach to reduce disability in patients with medication-overuse headache: A randomized controlled open-label trial.

Nielsen M, Carlsen LN, Munksgaard SB, Engelstoft IMS, Jensen RH, Bendtsen L.

Cephalalgia. 2019 Jun;39(7):863-872.

 

Treatment of medication overuse headache-A review.

Munksgaard SB, Madsen SK, Wienecke T.

Acta Neurol Scand. 2019 May;139(5):405-414.

 

Circulating nociceptin and CGRP in medication-overuse headache.

Munksgaard SB, Ertsey C, Frandsen E, Bendtsen L, Tekes K, Jensen RH.

Acta Neurol Scand. 2019 Mar;139(3):269-275.

 

Economic benefits of treating medication-overuse headache - results from the multicenter COMOESTAS project.

Jellestad PL, Carlsen LN, Westergaard ML, Munksgaard SB, Bendtsen L, Lainez M, Fadic R, Katsarava Z, Goicochea MT, Spadafora S, Jensen RH, Nappi G, Tassorelli C; COMOESTAS Consortium.

Cephalalgia. 2019 Feb;39(2):274-285.

 

Complete detoxification is the most effective treatment of medication-overuse headache: A randomized controlled open-label trial.

Carlsen LN, Munksgaard SB, Jensen RH, Bendtsen L.

Cephalalgia. 2018 Feb;38(2):225-236.

 

[Clinical presentation and treatment of medication-overuse headache].

Carlsen LN, Westergaard ML, Munksgaard SB, Bendtsen L, Jensen RH.

Ugeskr Laeger. 2016 Sep 26;178(39):V06160387.

 

Medication-overuse headache: a perspective review.

Westergaard ML, Munksgaard SB, Bendtsen L, Jensen RH.

Ther Adv Drug Saf. 2016 Aug;7(4):147-58.

 

Medication overuse headache in Europe and Latin America: general demographic and clinical characteristics, referral pathways and national distribution of painkillers in a descriptive, multinational, multicenter study.

Find NL, Terlizzi R, Munksgaard SB, Bendtsen L, Tassorelli C, Nappi G, Katsarava Z, Lainez M, Goicochea MT, Shand B, Fadic R, Spadafora S, Pagani M, Jensen R; COMOESTAS Consortium.

J Headache Pain. 2015;17:20.

 

Superior Orbital Fissure Syndrome and Ophthalmoplegia Caused by Varicella Zoster Virus with No Skin Eruption in a Patient Treated with Tumor Necrosis Alpha Inhibitor.

Jensen H, Thomsen ST, Hansen SS, Munksgaard SB, Lindelof M.

Case Rep Neurol. 2015 Oct 30;7(3):221-6.

 

Medication overuse headache.

Munksgaard SB, Jensen RH.

Headache. 2014 Jul-Aug;54(7):1251-7.

 

Disability, anxiety and depression associated with medication-overuse headache can be considerably reduced by detoxification and prophylactic treatment. Results from a multicentre, multinational study (COMOESTAS project).

Bendtsen L, Munksgaard S, Tassorelli C, Nappi G, Katsarava Z, Lainez M, Leston J, Fadic R, Spadafora S, Stoppini A, Jensen R; COMOESTAS Consortium.

Cephalalgia. 2014 May;34(6):426-33.

 

Modulation of central sensitisation by detoxification in MOH: results of a 12-month detoxification study.

Munksgaard SB, Bendtsen L, Jensen RH.

Cephalalgia. 2013 May;33(7):444-53.

 

Detoxification of medication-overuse headache by a multidisciplinary treatment programme is highly effective: a comparison of two consecutive treatment methods in an open-label design.

Munksgaard SB, Bendtsen L, Jensen RH.

Cephalalgia. 2012 Aug;32(11):834-44.

Treatment-resistant medication overuse headache can be cured.

Munksgaard SB, Bendtsen L, Jensen RH.

Headache. 2012 Jul-Aug;52(7):1120-9.

 

What do the patients with medication overuse headache expect from treatment and what are the preferred sources of information?

Munksgaard SB, Allena M, Tassorelli C, Rossi P, Katsarava Z, Bendtsen L, Nappi G, Jensen R; Comoestas Consortium.

J Headache Pain. 2011 Feb;12(1):91-6.